Replication of the Association of a MET Variant with Autism in a Chinese Han Population
Xue Zhou; Yang Xu; Jia Wang; Hongbo Zhou; Xian Liu; Qasim Ayub; Xuelai Wang; Chris Tyler‐Smith · 2011 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Autism is a common, severe and highly heritable neurodevelopmental disorder in children, affecting up to 100 children per 10,000. The MET gene has been regarded as a promising candidate gene for this disorder because it is located within a replicated linkage interval, is involved in pathways affecting the development of the cerebral cortex and cerebellum in ways relevant to autism patients, and has shown significant association signals in previous studies. PRINCIPAL FINDINGS: Here, we present new ASD patient and control samples from Heilongjiang, China and use them in a case-contro
Abstract by Xue Zhou; Yang Xu; Jia Wang; Hongbo Zhou; Xian Liu; Qasim Ayub; Xuelai Wang; Chris Tyler‐Smith, PLoS ONE (2011) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0027428