Null results of oxytocin and vasopressin administration on mentalizing in a large fMRI sample: evidence from a randomized controlled trial
Mark A. Straccia; Adam R. Teed; Perri L. Katzman; Kevin M. Tan; Michael H. Parrish; Michael R. Irwin; Naomi I. Eisenberger; Matthew D. Lieberman · 2021 · Psychological Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Although potential links between oxytocin (OT), vasopressin (AVP), and social cognition are well-grounded theoretically, most studies have included all male samples, and few have demonstrated consistent effects of either neuropeptide on mentalizing (i.e. understanding the mental states of others). To understand the potential of either neuropeptide as a pharmacological treatment for individuals with impairments in social cognition, it is important to demonstrate the beneficial effects of OT and AVP on mentalizing in healthy individuals. METHODS: = 186) of healthy individuals, we exa
Abstract by Mark A. Straccia; Adam R. Teed; Perri L. Katzman; Kevin M. Tan; Michael H. Parrish; Michael R. Irwin; Naomi I. Eisenberger; Matthew D. Lieberman, Psychological Medicine (2021) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1017/s0033291721004104