Comparison of KIT patterns and infiltration of eosinophils in canine mast cell tumor
C.D. Araújo; G.S. Sanches; F. Borek; D.C. Rocha; G.D. Giustina; J.R. Engracia Filho; G.H. Bechara · 2023 · Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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Abstract
ABSTRACT KIT protein is associated with the etiology of canine mast cell tumors (MCT); however, the expression patterns of KIT are highly variable. The aim of this study was to determine if KIT patterns are related with eosinophil count in MCT. Hematoxylin eosin and May Grünwald-Giemsa stain techniques were applied, histological grading and eosinophil counting were performed in 48 MCT samples. Immunohistochemical evaluation was performed with IL-5, VEGFr, and c-KIT antibodies. The percentage of immunolabeling with IL-5 and VEGFr was determined, and the samples incubated with c-KIT were graded
Abstract by C.D. Araújo; G.S. Sanches; F. Borek; D.C. Rocha; G.D. Giustina; J.R. Engracia Filho; G.H. Bechara, Arquivo Brasileiro de Medicina Veterinária e Zootecnia (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1590/1678-4162-12963