PCSK9 concentrations in different stages of subclinical atherosclerosis and their relationship with inflammation
Tóth Štefan; Olexa Peter; Hertelyová Zdenka; Štefanič Peter; Kopolovets Ivan; Berek Peter; Filip Vladimir; Chakravarty Ryan · 2020 · Open Chemistry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
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Abstract
The aim of this study was to detect the concentrations of PCSK9 in various subclinical stages of atherosclerosis and to highlight its relationship with inflammation. One hundred and fifty-nine healthy patients were divided into three groups, based on the extent of atherosclerotic changes in the carotid artery: a group without identifiable atherosclerosis, cIMT>75‰ and an asymptomatic plaque group. The PCSK9 was measured by ELISA and hsCRP by the immunoturbidimetric method. Vascular changes were identified by a carotid ultrasound. PCSK9 was elevated, when comparing the healthy group with the cI
Abstract by Tóth Štefan; Olexa Peter; Hertelyová Zdenka; Štefanič Peter; Kopolovets Ivan; Berek Peter; Filip Vladimir; Chakravarty Ryan, Open Chemistry (2020) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1515/chem-2020-0147