Highly ordered clustering of TNFα and BAFF ligand-receptor-intracellular adaptor complexes on a lipid membrane
Chan Seok Lim; Jisun Lee; Jisun Lee; Ji Won Kim; Jie‐Oh Lee; Jie‐Oh Lee · 2025 · Nature Communications
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
SUMMARY We report the cryo-EM structures of clusters of TNF receptor family proteins, TNFR1 and BAFFR. The receptor-ligand complexes were anchored to a flat lipid layer to mimic the membrane-bound state. We observed that the TNFα-TNFR1…
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Metadata source: OpenAlex · DOI 10.1038/s41467-025-61271-6