Gut Microbiota Modulation through Akkermansia spp . Supplementation Increases CAR T-cell Potency
Laura Marcos-Kovandzic; Michele Avagliano; Myriam Ben Khelil; Janesa Srikanthan; Rim Abdallah; Valentina Petrocelli; Jessica Rengassamy; Alexia Alfaro · 2025 · Cancer Discovery
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
This study investigates the clinical relevance of the gut microbiome at taxonomic and metabolic levels in anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, both in patients and in a preclinical syngeneic tumor model. Patients with…
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Metadata source: OpenAlex · DOI 10.1158/2159-8290.cd-24-1230