Synthesis of enantioenriched atropisomers by biocatalytic deracemization
Casey B. Roos; S. Luke Schulert; Lara E. Zetzsche; Spencer E. McMinn; Angela E. Cheong; Eunjae Shim; Eugene E. Kwan; Alison R. H. Narayan · 2025 · Nature
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
The synthesis of enantiopure materials is vital for pharmaceutical and agrochemical industries owing to the inherently chiral nature of biological systems and the fact that two enantiomers can have markedly different biochemical…
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Metadata source: OpenAlex · DOI 10.1038/s41586-025-09738-w