Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
Mohamad Saad; Ayman El‐Menyar; Khalid Kunji; Ehsan Ullah; Jassim Al Suwaidi; Iftikhar J. Kullo · 2022 · Circulation Genomic and Precision Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background: Enthusiasm for using polygenic risk scores (PRSs) in clinical practice is tempered by concerns about their portability to diverse ancestry groups, thus motivating genome-wide association studies in non-European ancestry…
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Metadata source: OpenAlex · DOI 10.1161/circgen.122.003712