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Negative / Null Result ReportOpen accessPsychology· cited by 115

Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: A randomized placebo-controlled pilot study

Suzanna M. Zick; Benjamin D. Wright; Ananda Sen; J. Todd Arnedt · 2011 · BMC Complementary and Alternative Medicine

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BACKGROUND: Despite being the most commonly used herbal for sleep disorders, chamomile's (Matricaria recutita) efficacy and safety for treating chronic primary insomnia is unknown. We examined the preliminary efficacy and safety of chamomile for improving subjective sleep and daytime symptoms in patients with chronic insomnia. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial in 34 patients aged 18-65 years with DSM-IV primary insomnia for ≥ 6-months. Patients were randomized to 270 mg of chamomile twice daily or placebo for 28-days. The primary outcomes were sle

Abstract by Suzanna M. Zick; Benjamin D. Wright; Ananda Sen; J. Todd Arnedt, BMC Complementary and Alternative Medicine (2011) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1186/1472-6882-11-78