Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: A randomized placebo-controlled pilot study
Suzanna M. Zick; Benjamin D. Wright; Ananda Sen; J. Todd Arnedt · 2011 · BMC Complementary and Alternative Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Despite being the most commonly used herbal for sleep disorders, chamomile's (Matricaria recutita) efficacy and safety for treating chronic primary insomnia is unknown. We examined the preliminary efficacy and safety of chamomile for improving subjective sleep and daytime symptoms in patients with chronic insomnia. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial in 34 patients aged 18-65 years with DSM-IV primary insomnia for ≥ 6-months. Patients were randomized to 270 mg of chamomile twice daily or placebo for 28-days. The primary outcomes were sle
Abstract by Suzanna M. Zick; Benjamin D. Wright; Ananda Sen; J. Todd Arnedt, BMC Complementary and Alternative Medicine (2011) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Our Princess Is in Another Castle
Negative / Null Result ReportUsing Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial
Negative / Null Result ReportHow Replicable Are Links Between Personality Traits and Consequential Life Outcomes? The Life Outcomes of Personality Replication Project
Negative / Null Result ReportThe cross-cultural validity of posttraumatic stress disorder: implications for DSM-5
Negative / Null Result ReportPsychiatric and medical correlates of DSM‐5 eating disorders in a nationally representative sample of adults in the United States
Negative / Null Result ReportRomantic relationships and the physical and mental health of college students
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1186/1472-6882-11-78
