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Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry

Comparing the synaptic potentiation in schaffer collateral-CA1 synapses in dorsal and intermediate regions of the hippocampus in normal and kindled rats

Maryam Sharifi; Shahrbanoo Oryan; Alireza Komaki; Victoria Barkley; Abdolrahman Sarihi; Javad Mirnajafi-Zadeh · 2023 · IBRO Neuroscience Reports

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

There is growing evidence that the hippocampus comprises diverse neural circuits that exhibit longitudinal variation in their properties, however, the intermediate region of the hippocampus has received comparatively little attention. Therefore, this study was designed to compared short- and long-term synaptic plasticity between the dorsal and intermediate regions of the hippocampus in normal and PTZ-kindled rats. Short-term plasticity was assessed by measuring the ratio of field excitatory postsynaptic potentials’ (fEPSPs) slope in response to paired-pulse stimulation at three different inter

Abstract by Maryam Sharifi; Shahrbanoo Oryan; Alireza Komaki; Victoria Barkley; Abdolrahman Sarihi; Javad Mirnajafi-Zadeh, IBRO Neuroscience Reports (2023) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1016/j.ibneur.2023.09.010