The extracellular matrix in inflammation and cancer
Wanting Zhang; Yuhang Xiang; Chen Lu; Fei Wang; He Ren; Hao Wu (65943); Meisi Yan · 2026 · Molecular Biomedicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The extracellular matrix (ECM) forms a dynamic structure around cells, providing environmental cues, mechanical support, and tissue protection. It is composed of fibrous proteins, glycosaminoglycans (GAGs), proteoglycans, and glycoproteins. The molecular, physical, and mechanical properties of the ECM regulate the motility, survival, and function of immune cells. In most cancers, inflammatory cytokines and proteases-particularly matrix metalloproteinases(MMPs)-released within the immune-infiltrated inflammatory microenvironment can remodel the ECM. Cytokines such as tumor necrosis factor-α (TN
Abstract by Wanting Zhang; Yuhang Xiang; Chen Lu; Fei Wang; He Ren; Hao Wu (65943); Meisi Yan, Molecular Biomedicine (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s43556-026-00415-6