MedNet-PVS: A MedNeXt-Based Deep Learning Model for Automated Segmentation of Perivascular Spaces
Zhen Xuen Brandon Low; Rory Zhang; Hang Min; William Pham; Lucy Vivash; Jasmine Moses; Miranda Lynch; Karina Dorfman · 2025 · arXiv
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Enlarged perivascular spaces (PVS) are increasingly recognized as biomarkers of cerebral small vessel disease, Alzheimer's disease, stroke, and aging-related neurodegeneration. However, manual segmentation of PVS is time-consuming and subject to moderate inter-rater reliability, while existing automated deep learning models have moderate performance and typically fail to generalize across diverse clinical and research MRI datasets. We adapted MedNeXt-L-k5, a Transformer-inspired 3D encoder-decoder convolutional network, for automated PVS segmentation. Two models were trained: one using a homog
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Metadata source: arXiv