Characterisation of osteogenic and vascular responses of hMSCs to Ti-Co doped phosphate glass microspheres using a microfluidic perfusion platform
Carlotta Peticone; David De Silva Thompson; Nikolay Dimov; Ben Jevans; Nick Glass; Martina Micheletti; Jonathan C Knowles; Hae-Won Kim · 2020 · Journal of Tissue Engineering
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Using microspherical scaffolds as building blocks to repair bone defects of specific size and shape has been proposed as a tissue engineering strategy. Here, phosphate glass (PG) microcarriers doped with 5 mol % TiO 2 and either 0 mol % CoO (CoO 0%) or 2 mol % CoO (CoO 2%) were investigated for their ability to support osteogenic and vascular responses of human mesenchymal stem cells (hMSCs). Together with standard culture techniques, cell-material interactions were studied using a novel perfusion microfluidic bioreactor that enabled cell culture on microspheres, along with automated processin
Abstract by Carlotta Peticone; David De Silva Thompson; Nikolay Dimov; Ben Jevans; Nick Glass; Martina Micheletti; Jonathan C Knowles; Hae-Won Kim, Journal of Tissue Engineering (2020) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1177/2041731420954712