Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains
Anna Müller; Michaela Wenzel; Henrik Strahl; Fabian Grein; Terrens N. V. Saaki; Bastian Kohl; Tjalling Siersma; Julia E. Bandow · 2016 · Proceedings of the National Academy of Sciences
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
and different assays, including proteomics, ionomics, and fluorescence light microscopy. We found that daptomycin causes a gradual decrease in membrane potential but does not form discrete membrane pores. Although we found no evidence for…
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Metadata source: OpenAlex · DOI 10.1073/pnas.1611173113