e-ISSN: Pending
Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology

Long term outcomes of pituitary adenomas in Multiple Endocrine Neoplasia type 1: a nationwide study

Nuria Valdés; Nuria Valdés; Ana Romero; Estrella Diego; María Calatayud; Cristina Lamas; Marta Araujo-Castro; Cristina Álvarez-Escolá · 2024 · Frontiers in Endocrinology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

IntroductionHistorically, Multiple Endocrine Neoplasia type 1 (MEN1)-related pituitary adenomas (PAs) were considered more aggressive and treatment-resistant than sporadic PAs. However, recent studies suggest similarities in their behavior. This study aimed to evaluate the long-term outcomes of MEN1 PAs and identify predictive factors.MethodsNationwide multicenter retrospective cohort study of MEN1-related PAs with a minimum 1-year follow-up, collecting patient demographics, germline MEN1 pathogenic variants (PV), PA size, secretory profile, radiological characteristics, treatments, and outcom

Abstract by Nuria Valdés; Nuria Valdés; Ana Romero; Estrella Diego; María Calatayud; Cristina Lamas; Marta Araujo-Castro; Cristina Álvarez-Escolá, Frontiers in Endocrinology (2024) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3389/fendo.2024.1427821