Vibration therapy as an effective approach to improve bone healing in diabetic rats
Maysa S. Campos; José B. Volpon; João Paulo B. Ximenez; João Paulo B. Ximenez; Ana Paula Franttini; Christopher E. Dalloul; Manoel D. Sousa-Neto; Raquel A. Silva · 2022 · Frontiers in Endocrinology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
ObjectiveTo investigate the effects of vibration therapy on fracture healing in diabetic and non-diabetic rats.Methods148 rats underwent fracture surgery and were assigned to four groups: (1) SHAM: weight-matched non-diabetic rats, (2) SHAM+VT: non-diabetic rats treated with vibration therapy (VT), (3) DM: diabetic rats, and (4) DM+VT: diabetic rats treated with VT. Thirty days after diabetes induction with streptozotocin, animals underwent bone fracture, followed by surgical stabilization. Three days after bone fracture, rats began VT. Bone healing was assessed on days 14 and 28 post-fracture
Abstract by Maysa S. Campos; José B. Volpon; João Paulo B. Ximenez; João Paulo B. Ximenez; Ana Paula Franttini; Christopher E. Dalloul; Manoel D. Sousa-Neto; Raquel A. Silva, Frontiers in Endocrinology (2022) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fendo.2022.909317