Cardiometabolic phenotypes and mitochondrial DNA copy number in two cohorts of UK women
Anna L. Guyatt; Kimberley Burrows; Philip A. I. Guthrie; Sue Ring; Wendy L. McArdle; Ian N.M. Day; Raimondo Ascione; Debbie A. Lawlor · 2017 · Mitochondrion
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The mitochondrial genome is present at variable copy number between individuals. Mitochondria are vulnerable to oxidative stress, and their dysfunction may be associated with cardiovascular disease. The association of mitochondrial DNA copy number with cardiometabolic risk factors (lipids, glycaemic traits, inflammatory markers, anthropometry and blood pressure) was assessed in two independent cohorts of European origin women, one in whom outcomes were measured at mean (SD) age 30 (4.3) years (N=2278) and the second at 69.4 (5.5) years (N=2872). Mitochondrial DNA copy number was assayed by qua
Abstract by Anna L. Guyatt; Kimberley Burrows; Philip A. I. Guthrie; Sue Ring; Wendy L. McArdle; Ian N.M. Day; Raimondo Ascione; Debbie A. Lawlor, Mitochondrion (2017) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1016/j.mito.2017.08.007