A Genome-Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos
Kristin M. Burkart; Tamar Sofer; Stephanie J. London; Ani Manichaikul; Fernando Pires Hartwig; Qi Yan; María Soler Artigas; Lydiana Ávila · 2018 · American Journal of Respiratory and Critical Care Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Rationale Lung function and chronic obstructive pulmonary disease (COPD) are heritable traits. Genome-wide association studies (GWAS) have identified numerous pulmonary function and COPD loci, primarily in cohorts of European ancestry. Objectives Perform a GWAS of COPD phenotypes in Hispanic/Latino populations to identify loci not previously detected in European populations. Methods GWAS of lung function and COPD in Hispanic/Latino participants from a population-based cohort. We performed replication studies of novel loci in independent studies. Measurements and Main Results Among 11,
Abstract by Kristin M. Burkart; Tamar Sofer; Stephanie J. London; Ani Manichaikul; Fernando Pires Hartwig; Qi Yan; María Soler Artigas; Lydiana Ávila, American Journal of Respiratory and Critical Care Medicine (2018) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1164/rccm.201707-1493oc