Psychedelic Therapy vs Antidepressants for the Treatment of Depression Under Equal Unblinding Conditions
Zachary J. Williams; Hannah Barnett; Balázs Szigeti · 2026 · JAMA Psychiatry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Importance: Psychedelic-assisted therapy (PAT) trials have high levels of functional unblinding, which biases results when comparing PAT with blinded interventions. Because PAT is effectively always open label, treatment results should be…
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WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1001/jamapsychiatry.2025.4809