Smartphone-Based Peptide Nucleic Acid (PNA) Probe-Assisted Potentiometric Biosensor for Point-of-Care Testing of SARS-CoV-2 Nucleic Acid
Tuğba Özer; Sakda Jampasa; Atchara Lomae; Nipapan Ruecha; Osman Sağdıç; Tirayut Vilaivan; Charles S. Henry; Orawon Chailapakul · 2026 · Analytical Chemistry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
High Resolution Image Download MS PowerPoint Slide Herein, we present a potentiometric biosensor based on amine magnetic beads functionalized with electrostatically neutral peptide nucleic acids (PNA) for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A screen-printed carbon electrode was modified with a plasticized polymeric membrane. A SARS-CoV-2 specific peptide nucleic acid probe was designed and synthesized. We exploited the advantage of neutral PNAs to remove the negatively charged DNA probes that cause fouling due to the attraction of positively charged b
Abstract by Tuğba Özer; Sakda Jampasa; Atchara Lomae; Nipapan Ruecha; Osman Sağdıç; Tirayut Vilaivan; Charles S. Henry; Orawon Chailapakul, Analytical Chemistry (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1021/acs.analchem.6c00766