Mapping intratumor heterogeneity across layers for advancing immunotherapy
Jean‐Christophe Marine; Osnat Bartok; Shira Sagie; Pietro Paolo Vitiello; Alberto Bardelli; Chen Weller; Tiangen Chang; Claudia Tonelli · 2026 · Cell
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Intratumor heterogeneity (ITH) encompasses genetic, epigenetic, transcriptional, proteomic, and immunopeptidomic diversity. Beyond genetic heterogeneity, it is increasingly clear that non-mutational heterogeneity and plasticity generate…
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Metadata source: OpenAlex · DOI 10.1016/j.cell.2026.03.025