Computational Transcriptional Deconvolution and Purity-Corrected Analysis Characterizes Invasion Programs in IDH-Wildtype Glioblastoma: Proneural Distinctiveness, Transcription Factor Proxy Activity, and Dual Mechanisms of Therapeutic Resistance
Saadawy M; Elkoumi O; Saadawy E · 2026 · Preprint
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
Abstract Background Glioblastoma (GBM) recurrence originates from the non-resectable invasive margin. While the Mesenchymal (ME) subtype has traditionally been considered the most invasive, this assignment is confounded by tumor purity and…
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Metadata source: Europe PMC · DOI 10.21203/rs.3.rs-9716905/v1