Neutrophils shape the therapeutic efficacy of sirtuin 1 activity modulators in murine influenza virus infection.
Simeonova L; Leseva M; Stoyanov K; Mai A; Saso L; Dimitrova P · 2025 · Biochimica et biophysica acta. Molecular basis of disease
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Sirtuin 1 (Sirt1), a class III histone deacetylase, is a key regulator of gene expression in various immune cell types, including neutrophils, during infection and acute inflammation. Herein, we studied the effect of the Sirt1 activator…
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Metadata source: Europe PMC · DOI 10.1016/j.bbadis.2025.167915