Long-Term Outcomes of Left Bundle-Branch Pacing vs Biventricular Pacing in Heart Failure
Xueying Chen; Xi Liu; Ruogu Li; Zhongkai Wang; Yixiu Liang; Lei Zhang; Wei Wang; Jin Bai · 2026 · JAMA Cardiology
WASTE classifies this as Replication Failure · AI classification, approximate
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Abstract
Importance: Left bundle-branch pacing (LBBP) has been proposed as an alternative to biventricular pacing (BiVP) for patients with heart failure with left bundle-branch block (LBBB). However, robust clinical evidence from randomized clinical trials is lacking. Objective: To evaluate the long-term clinical outcomes of LBBP and BiVP. Design, Setting, and Participants: This multicenter, prospective, randomized clinical trial enrolled 200 patients at 6 centers in China with a left ventricular ejection fraction (LVEF) of 35% or less and LBBB from October 2020 to March 2022. This study was took place
Abstract by Xueying Chen; Xi Liu; Ruogu Li; Zhongkai Wang; Yixiu Liang; Lei Zhang; Wei Wang; Jin Bai, JAMA Cardiology (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1001/jamacardio.2026.0083