Association between initial norepinephrine dose and minute by minute mean arterial pressure.
Nishikimi M; Ohshimo S; Nobayashi K; Kinoshita T; Shime N · 2026 · Critical care (London, England)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Neither the magnitude nor the timing of mean arterial pressure (MAP) increase after norepinephrine (NE) initiation is well defined, leaving clinicians without clear criteria for adequate starting doses. This study aimed to…
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Metadata source: Europe PMC · DOI 10.1186/s13054-026-05920-2