Correlation between Vitamin D Receptor Gene FOKI and BSMI Polymorphisms and the Susceptibility to Pulmonary Tuberculosis in an Indonesian Batak-ethnic Population
Bintang Y.M. Sinaga; Muhammad Amin; Yahwardiah Siregar; Sori M Sarumpaet · 2014 · Acta Medica Indonesiana
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Abstract
Aim: to explore the role of FokI and BsmI polymorphisms the VDR gene in the susceptibility to pulmonary tuberculosis (PTB) in an Indonesian Batak ethnic population. Methods: matched case-control study was conducted on 76 PTB patients and 76 healthy normal control. Genetic polymorphisms of Vitamin D Receptor (VDR) gene were analysed using PCR-RFLP. Results: the frequencies of FokI genotypes were FF 35.5%, Ff 55.3%, ff 9.2% for PTB patients and FF 39.5%, Ff 44.7.% and ff 15.8% for normal control. The BsmI genotypes frequencies were BB 0%, Bb 68.4%, bb 31.6% for TB patients and BB 2.6%, Bb 23.7%
Abstract by Bintang Y.M. Sinaga; Muhammad Amin; Yahwardiah Siregar; Sori M Sarumpaet, Acta Medica Indonesiana (2014) — licensed CC BY 4.0.
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