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Negative / Null Result ReportOpen accessMedicine· cited by 130

Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival

Alan K. Burnett; Nigel H. Russell; Ann E. Hunter; Donald Milligan; Steven Knapper; Keith Wheatley; John Yin; Mary Frances McMullin · 2013 · Blood

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Better treatment is required for older patients with acute myeloid leukemia (AML) not considered fit for intensive chemotherapy. We report a randomized comparison of low-dose Ara-C (LDAC) vs the novel nucleoside, clofarabine, in untreated…

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Metadata source: OpenAlex · DOI 10.1182/blood-2013-04-496596