No evidence for altered plasma NGF and BDNF levels in fibromyalgia patients
David Baumeister; Wolfgang Eich; Silvia Saft; Olga Geisel; Rainer Hellweg; Anja Finn; Camilla I. Svensson; Jonas Tesarz · 2019 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
There has been a surging interest in the putative role of peripheral growth factors in the pathophysiology of fibromyalgia, specifically in the peripheral sensitization that occurs in chronic pain disorders. This cross-sectional study set out to assess and compare brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in plasma samples from fibromyalgia patients and healthy controls. Plasma BDNF and NGF were measured in 89 fibromyalgia patients and 36 pain-free controls, and compared using ANCOVA controlling for potential confounders, as well as Bayesian methods for parameter e
Abstract by David Baumeister; Wolfgang Eich; Silvia Saft; Olga Geisel; Rainer Hellweg; Anja Finn; Camilla I. Svensson; Jonas Tesarz, Scientific Reports (2019) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41598-019-49403-7