Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials.
Gonzalez DE; Dickerson BL; Hines K; Chun J; Gil A; Forbes SC; Candow DG; Kreider RB · 2026 · Sports (Basel, Switzerland)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. This analysis investigated whether the dose or duration of CrM was associated with SEs.…
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Metadata source: Europe PMC · DOI 10.3390/sports14040137