Negative / Null Result ReportOpen accessMedicine

Association of outpatient use of renin–angiotensin–aldosterone system blockers on outcomes of acute respiratory illness during the COVID-19 pandemic: a cohort study

Molly Moore Jeffery; Lucas Oliveira J e Silva; Fernanda Bellolio; Nathan W Cummins; Timothy M Dempsey; Vesna D Garovic; Andrew Limper · 2022 · BMJ Open

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD

Abstract by Molly Moore Jeffery; Lucas Oliveira J e Silva; Fernanda Bellolio; Nathan W Cummins; Timothy M Dempsey; Vesna D Garovic; Andrew Limper, BMJ Open (2022) — licensed CC BY 4.0.

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