Exploration of shared genetic susceptibility loci between type 1 diabetes and rheumatoid arthritis in the Pakistani population
Muhammad Muaaz Aslam; Peter John; Kang-Hsien Fan; Attya Bhatti; Sidrah Jahangir; Eleanor Feingold; F. Yesim Demirci; M. Ilyas Kamboh · 2019 · BMC Research Notes
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
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Abstract
Abstract Objective Type 1 diabetes (T1D) and rheumatoid arthritis (RA) are autoimmune diseases. It is known that certain genetic loci and factors that increase the overall autoimmunity risk can be shared among different autoimmune diseases. We sought to replicate seven T1D-related SNPs (single nucleotide polymorphisms) that have been previously reported to be associated with RA susceptibility in a small set of mixed family-based and case–control Pakistani sample in a relatively large and independent RA case–control sample from the same population. Seven T1D-associated SNPs (GLIS3/rs7020673, BA
Abstract by Muhammad Muaaz Aslam; Peter John; Kang-Hsien Fan; Attya Bhatti; Sidrah Jahangir; Eleanor Feingold; F. Yesim Demirci; M. Ilyas Kamboh, BMC Research Notes (2019) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s13104-019-4590-8