e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine· cited by 221

Immune dysregulation in sepsis: experiences, lessons and perspectives

Min Cao; Guozheng Wang; Jianfeng Xie · 2023 · Cell Death Discovery

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host responses to infection. Not only does sepsis pose a serious hazard to human health, but it also imposes a substantial economic burden on the healthcare system. The cornerstones of current treatment for sepsis remain source control, fluid resuscitation, and rapid administration of antibiotics, etc. To date, no drugs have been approved for treating sepsis, and most clinical trials of potential therapies have failed to reduce mortality. The immune response caused by the pathogen is complex, resulting in a dysregul

Abstract by Min Cao; Guozheng Wang; Jianfeng Xie, Cell Death Discovery (2023) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1038/s41420-023-01766-7