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Negative / Null Result ReportOpen accessMedicine

Reassessment of the Collaborative Normal-Tension Glaucoma Study: Statistical Evidence and Implications for Current Management.

Killer HE; Pircher A; Stekhoven DJ · 2026 · Ophthalmology and therapy

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Introduction The Collaborative Normal-Tension Glaucoma Study (CNTGS) is frequently cited as evidence that a 30% reduction in intraocular pressure (IOP) slows progression in normal-tension glaucoma (NTG). This study re-examines the…

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Metadata source: Europe PMC · DOI 10.1007/s40123-025-01300-1