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Negative / Null Result ReportOpen accessMedicine

Prognostic follow-up of high-grade squamous intraepithelial lesions of the cervix near the conization margin: A retrospective cohort study.

Dandan Chen; Huamin Wu; Feifeng Huang; Kailiang Tan · 2025 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Objective This study explored the prognosis of high-grade squamous intraepithelial lesion (HSIL) patients with negative margins, investigating the impact of different distances between lesions and incisal margins in conization specimens. Methods This retrospective cohort study included 240 HSIL patients. Patients with negative incisal margins were divided into 3 groups according to the distance between the lesion and the incisal margin in the conization tissue. Group 1 consisted of a distance of 3 mm (n = 202). For patients with lesions close to the incisal margin (≤3 cm), the decision between

Abstract by Dandan Chen; Huamin Wu; Feifeng Huang; Kailiang Tan, PLoS ONE (2025) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1371/journal.pone.0331184