Performance of the Self-Controlled Case Series With Active Comparators for Drug Safety Signal Detection Using Merative MarketScan Research Databases.
Coste A; Wong AYS; Haguinet F; Bate A; Douglas IJ · 2025 · Pharmacoepidemiology and drug safety
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Despite testing of epidemiological methods in US Claims databases for signal detection, such data sources have not become a routine capability. The Self Controlled Case Series (SCCS) is one of the most promising methods for drug…
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Metadata source: Europe PMC · DOI 10.1002/pds.70250