Nous-209 neoantigen vaccine for cancer prevention in Lynch syndrome carriers: a phase 1b/2 trial
Anna Morena D’Alise; Jason Willis; Fahriye Duzagac; Michael J. Hall; M. Cruz-Correa; Gregory Idos; Selvi Thirumurthi; Veroushka Ballester · 2026 · Nature Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Cancer interception is a preventative approach aiming to reduce cancer incidence by targeting precancers and early-stage cancers. Lynch syndrome (LS) is a prevalent hereditary cancer syndrome affecting ~1 in 300 individuals, with an…
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Metadata source: OpenAlex · DOI 10.1038/s41591-025-04182-9