In-situ-forming zwitterionic hydrogel does not ameliorate osteoarthritis in vivo, despite protective effects ex vivo.
Asadikorayem M; Weber P; Zhang S; Surman F; Fercher D; Fonti M; Bevc K; Kauppinen S · 2025 · Biomaterials advances
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Osteoarthritis (OA) is one of the most common degenerative joint diseases, with no effective therapeutic options available. In this study, we aimed to develop an interpenetrating, in-situ-forming hydrogel based on biocompatible and…
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Metadata source: Europe PMC · DOI 10.1016/j.bioadv.2024.214151