The recent clinical trial of losmapimod for the treatment of facioscapulohumeral muscular dystrophy.
Bloch RJ; Traficante M; Mariot V; Dumonceaux J · 2025 · Neuromuscular disorders : NMD
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Facioscapulohumeral muscular dystrophy is a progressive muscle disorder that is likely linked to aberrant DUX4 expression. Losmapimod, a p38 kinase inhibitor, was utilized to suppress DUX4 and its downstream effects. Phase I/II clinical…
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Metadata source: Europe PMC · DOI 10.1016/j.nmd.2025.105422