The role of proinflammatory response and the kynurenine pathway in the association between childhood maltreatment and lifetime substance use disorder.
Östman L; Paul ER; Zhang H; Larsson E; Perini I; Schwieler L; Erhardt S; Holm L · 2026 · Neurobiology of stress
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Introduction Childhood maltreatment (CM) is a risk factor for adult psychiatric and substance use disorders (SUD). Retrospectively assessed CM has been linked to increased proinflammatory cytokines, including IL-6. Induced by inflammation,…
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Metadata source: Europe PMC · DOI 10.1016/j.ynstr.2026.100820