Negative / Null Result ReportOpen accessMedicine

HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B.

Rong Zhong; Yao Tian; Li Liu; Qian Qiu; Ying Wang; Rui Rui; Bei-Fang Yang; Sheng-Yu Duan · 2012 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

A recent genome-wide association study has identified a new susceptibility locus, kinesin family member 1B gene (KIF1B), strongly associated with progression from chronic hepatitis B (CHB) to hepatitis B virus-related hepatocellular carcinoma (HCC) in Chinese population, this study was carried out to explore the role of the genetic variants in KIF1B in the development of chronic hepatitis B.Three KIF1B polymorphisms (rs8019, rs17401924, and rs17401966) were selected and genotyped in 473 CHB patients and 580 controls with no history of CHB. Odds ratios (ORs) and 95% confidence intervals (CIs) w

Abstract by Rong Zhong; Yao Tian; Li Liu; Qian Qiu; Ying Wang; Rui Rui; Bei-Fang Yang; Sheng-Yu Duan, PLoS ONE (2012) — licensed CC BY 4.0.

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