CEOP/IVE/GDP alternating regimen compared with CEOP as the first-line therapy for newly diagnosed patients with peripheral T cell lymphoma: results from a phase 2, multicenter, randomized, controlled clinical trial
Ming-Ci Cai; Shu Cheng; Xin Wang; Jianda Hu; Yongping Song; Yao‐Hui Huang; Zi‐Xun Yan; Yujie Jiang · 2020 · Genome Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP)/CHOP-like chemotherapy is widely used in peripheral T cell lymphoma (PTCL). Here we conducted a phase 2, multicenter, randomized, controlled trial, comparing the efficacy and safety of CEOP/IVE/GDP alternating regimen with CEOP in newly diagnosed PTCL. Methods PTCL patients, except for anaplastic large cell lymphoma-anaplastic lymphoma kinase positive, were 1:1 randomly assigned to receive CEOP/IVE/GDP (CEOP, cyclophosphamide 750 mg/m 2 , epirubicin 70 mg/m 2 , vincristine 1.4 mg/m 2 [maximum 2 mg] on day 1
Abstract by Ming-Ci Cai; Shu Cheng; Xin Wang; Jianda Hu; Yongping Song; Yao‐Hui Huang; Zi‐Xun Yan; Yujie Jiang, Genome Medicine (2020) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s13073-020-00739-0