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Negative / Null Result ReportOpen accessMedicine· cited by 10

Astrocytes mobilize a broader repertoire of lysosomal repair mechanisms than neurons

Erin Murphy Smith; Natalí L. Chanaday; Sandra Maday · 2026 · iScience

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Lysosomal damage impairs proteostasis and contributes to neurodegenerative diseases, yet cell-type-specific differences in lysosomal repair remain unclear. Using a neuron-astrocyte coculture system, we compared responses to lysosomal…

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Metadata source: OpenAlex · DOI 10.1016/j.isci.2026.116866