Prehospital Whole Blood in Traumatic Hemorrhage — A Randomized Controlled Trial
Jason Smith; Rebecca Cardigan; Emily Sanderson; Laura Silsby; Claire Rourke; Ed BG Barnard; Peter Basham; Grazia Antonacci · 2026 · New England Journal of Medicine
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
BACKGROUND: Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. METHODS: We conducted a pragmatic,…
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Metadata source: OpenAlex · DOI 10.1056/nejmoa2516043