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Negative / Null Result ReportOpen accessMedicine· cited by 93

Distribution and Inhibition of Liposomes on Staphylococcus aureus and Pseudomonas aeruginosa Biofilm

Dong Dong; Nicky Thomas; Benjamin Thierry; Sarah Vreugde; Clive A. Prestidge; Peter‐John Wormald · 2015 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BACKGROUND: Staphylococcus aureus and Pseudomonas aeruginosa are major pathogens in chronic rhinosinusitis (CRS) and their biofilms have been associated with poorer postsurgical outcomes. This study investigated the distribution and anti-biofilm effect of cationic (+) and anionic (-) phospholipid liposomes with different sizes (unilamellar and multilamellar vesicle, ULV and MLV respectively) on S. aureus and P. aeruginosa biofilms. METHOD: Specific biofilm models for S. aureus ATCC 25923 and P. aeruginosa ATCC 15692 were established. Liposomal distribution was determined by observing SYTO9 sta

Abstract by Dong Dong; Nicky Thomas; Benjamin Thierry; Sarah Vreugde; Clive A. Prestidge; Peter‐John Wormald, PLoS ONE (2015) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0131806