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Failed Experiment ReportMedicine

Impact of ETI therapy on bone health, body composition and cardiopulmonary fitness in children with CF.

Holden A; Burns P; Devenny A; Thomson L; Langley R; Shepherd S; Mason A · 2026 · Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

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An experimental approach did not work as intended — learn what to avoid before investing the same effort.

Abstract (excerpt)

Background Improved survival in cystic fibrosis (CF) has shifted clinical focus toward late complications, including altered body composition, bone health and cardiopulmonary fitness. The effects of Elexacaftor/Tezacaftor/Ivacaftor (ETI)…

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Metadata source: Europe PMC · DOI 10.1016/j.jcf.2026.05.013