Renin, Aldosterone, and Treatment Response to Dapagliflozin, Spironolactone, and Their Combination: An Analysis From SOGALDI-PEF.
Ferreira; Marques; Neves; Leite; Teixeira; Saraiva; Sharma; Zannad · 2026 · JACC. Heart failure
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Hypertension and heart failure with preserved ejection fraction (HFpEF) often coexist, and sodium retention is a common feature of both conditions. Renin levels are suppressed in the setting of sodium overload and may modulate the blood…
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Metadata source: PubMed · DOI 10.1016/j.jchf.2026.103111