No Association of ABCB1 C3435T Genotype With Clopidogrel Response or Risk of Stent Thrombosis in Patients Undergoing Coronary Stenting
Juliane Jaitner; Tanja Morath; Robert A. Byrne; Siegmund Braun; Daniela Gebhard; Isabell Bernlochner; S. Schulz; Julinda Mehilli · 2012 · Circulation Cardiovascular Interventions
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: The prodrug clopidogrel requires intestinal absorption by the efflux pump P-glycoprotein MDR1 (multidrug resistant-1), encoded by the ABCB1 gene. Prior studies suggested that a common and functional genetic variant (C3435T,…
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Metadata source: OpenAlex · DOI 10.1161/circinterventions.111.965400