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Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology

Effect of preoperative estrogen on complications after proximal hypospadias repair: A randomized controlled trial

Akash Bihari Pati; Pritinanada Mishra; Santosh K Mahalik; Bikasha Bihary Tripathy; Manoj Kumar Mohanty · 2023 · Indian Journal of Urology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Introduction: Proximal hypospadias repair has many postoperative complications such as urethrocutaneous fistulae, wound dehiscence, and urethral stricture. The beneficial effect of estrogen to promote wound healing has been known. We designed a study to determine whether preoperative stimulation of tissue with estrogen can reduce the postoperative complications associated with wound healing in patients undergoing hypospadias repair. Methods: Patients with proximal hypospadias requiring two-stage repairs (chordee correction followed by urethral tubularization) were randomized to estrogen and co

Abstract by Akash Bihari Pati; Pritinanada Mishra; Santosh K Mahalik; Bikasha Bihary Tripathy; Manoj Kumar Mohanty, Indian Journal of Urology (2023) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.4103/iju.iju_387_22