e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine

Serum biomarkers remain stable after transitioning from intravenous to subcutaneous natalizumab in multiple sclerosis.

Muñoz-Vendrell A; Arroyo-Pereiro P; León I; Bau L; Matas E; Romero-Pinel L; Roca-Pereira S; Martínez-Yélamos A · 2026 · Journal of neurology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Background Subcutaneous natalizumab offers greater convenience than intravenous administration, but pharmacokinetic differences have raised concerns about potential subclinical disease activity. Serum neurofilament light chain (sNfL) and…

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Metadata source: Europe PMC · DOI 10.1007/s00415-026-13949-0