Is Combined Tranexamic Acid Administration Superior to Single-Route Protocols in Primary Total Knee Arthroplasty? A Prospective Cohort Study.
Stepanovic Z; Ristic B; Matic A; Prodanovic N; Milosevic J; Stojadinovic I; Andric N; Prodanovic T · 2026 · Journal of clinical medicine
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Background : The optimal route of tranexamic acid (TXA) administration remains one of the most debated topics in total knee arthroplasty. This study aimed to compare the effects of intravenous (IV), intra-articular (IA), and combined TXA…
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Metadata source: Europe PMC · DOI 10.3390/jcm15124776